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Jul 2026

In Silico Design of High-Affinity Antibody VRC34.01 for HIV-1 Fusion Peptide Recognition.

The broadly neutralizing antibody VRC34.01, isolated from donor N123, recognizes the N-terminal fusion peptide of the HIV-1 envelope glycoprotein gp41 and inhibits viral membrane fusion. A detailed molecular understanding of this interaction is essential for elucidating the basis of peptide recognition and guiding anti...

Mei Feng, Nan Wang, Yi Song et al. · 0 citations

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