The source-preserving M-S-M-T framework prioritizes candidate multi-target links between gut microbiota-derived metabolites and OP-related inflammatory and bone-remodeling pathways, with AKT1 as one, rather than the unique, candidate signaling hub.
Wen-Xing Zeng, Yuan Gong, Yi-Tao Liao et al.· International Microbiology· 0 citations
A narrative synthesis of current evidence about the molecular mechanisms by which T-cell subsets regulate osteoporosis-related bone remodeling, the features of immune imbalance in different types of osteoporosis, T-cell-targeted intervention strategies, and translational challenges is provided to provide a theoretical...
Yuan Gong, Wen-Xing Zeng, Yi-Tao Liao et al.· Frontiers in Immunology· 0 citations
Background Osteoporotic vertebral compression fractures (OVCFs) predominantly cluster at the thoracolumbar junction (T11-L1). Recent studies suggest that both bone quality and muscle health significantly contribute to vertebral collapse. However, among numerous multidimensional imaging metrics, which one can most accur...
Yi-tao Liao, Xing-Guo Zhang, Xuanyu Xie et al.· Frontiers in Endocrinology· 0 citations
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