Author

Yi-Tian Xu

2 papers indexed here

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Open access Sep 2026

Local lactate-driven H3K18 lactylation impairs anti-influenza immunity through NRF2-dependent dendritic cell dysfunction.

Metabolic alterations are increasingly recognized during influenza virus infection, but how local lactate accumulation shapes antiviral immunity remains poorly characterized. By integrating time-series targeted energy metabolomics, single-cell RNA sequencing, flow cytometry, and functional perturbation, we show that in...

C. Lyu, Jiu-Yang Xu, Yu-Lin Zhang et al. · Cell Reports · 0 citations

Open access Sep 2026

Heterogeneity of the T & NK cell microenvironment in PBMCs and BALF from critical patients with COVID-19

Numerous single-cell RNA sequencing (scRNA-seq) studies have been conducted in the field of COVID-19 immunology, with a predominant focus on peripheral blood mononuclear cells (PBMCs). In contrast, longitudinal investigations of the pulmonary microenvironment have posed substantial clinical and technical challenges. He...

Hong-Ping Wu, Hong-Yu Liu, Ying Zheng et al. · Immunity & Inflammation · 0 citations