Biomanufacturing of 2-Pyrone-4,6-dicarboxylic Acid by an Engineered Corynebacterium glutamicum Cell Factory
2-Pyrone-4,6-dicarboxylic acid (PDC) is a promising pseudo-aromatic bio-based monomer for the production of biodegradable polyesters. Here, we combined metabolic engineering with fermentation process optimization to establish efficient de novo PDC biosynthesis in Corynebacterium glutamicum. To enhance the availability...