Open access
Aug 2026
A Stress-Adaptive Lipid Kinase Axis Defines Metabolic Vulnerabilities in Neuroendocrine Prostate Cancer
Findings reveal a metabolic adaptation in NEPC and provide preclinical evidence that co-targeting PIKfyve and FASN can overcome hypoxia-associated stress adaptation.
Yang Zheng, Caleb Cheng, Yizhi Cao et al.
· Cancer Cell · 0 citations