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Author

Yi Wang

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Sep 2026

Cancer-associated fibroblast-enriched TAGLN orchestrates HGF/c-MET-dependent transcriptional reprogramming in gastric cancer.

A CAF-TAGLN/HGF/c-MET/DDX5/CAV1 signaling cascade linking stromal activation to tumor-cell transcriptional reprogramming and CAF-tumor crosstalk within the TME is defined to identify TAGLN as a potential therapeutic vulnerability for microenvironment-directed intervention in GC.

Qiang Li, Jia-Ning Yang, Lu-Hong Cao et al. · 0 citations

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