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Review Open access Oct 2026

From CAF subtypes to clinically relevant states: cancer-associated fibroblasts in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) develops within a dense, poorly perfused tumor microenvironment (TME) in which cancer-associated fibroblasts (CAFs) are prominent cellular and structural components. Once viewed as a uniform population of activated matrix-producing cells, CAFs now include myofibroblastic, inflamm...

Yi Hao, Yi Wang, Qin-Yang Du et al. · 0 citations

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