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Open access Oct 2026

Activation of CaMKIIα regulates hippocampal mitochondrial metabolism and attenuates neuroinflammation: A novel therapeutic target for obesity-associated neurocognitive disorders.

ABSTRACT Obesity is strongly associated with cognitive impairment, especially in memory. However, the underlying molecular mechanisms remain unclear. Ca2+/calmodulin-dependent protein kinase II (CaMKII), a key synaptic kinase, regulates synaptic plasticity and hippocampal memory function through N-methyl-D-aspartate re...

Fan Liu, Chen Chen, Yu-Bing Zeng et al. · 0 citations
Review Open access Sep 2026

Regulatory T-cell remodeling across the HBV infection–cirrhosis continuum

Regulatory T cells (Tregs) have varied functions in the course of hepatitis B virus (HBV) infection and cirrhosis. Regulatory T cells (Tregs) generally restrict excessive immune-mediated liver injury in acute HBV infection but may also inhibit antiviral immunity. During chronic infection, expanded and intrahepatically...

Yu-Dan Fu, Yi Wang, Ji-Qi Ouyang et al. · 0 citations

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