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Review Open access Sep 2026

Inflammatory pathways in cerebral ischemia- reperfusion injury: Focus on the NLRP3 inflammasome

Cerebral ischemia-reperfusion injury (CIRI) is a severe neurological disorder characterized by exacerbated brain tissue damage and deteriorated neurological function following the restoration of blood flow after ischemia. The NLRP3 inflammasome, a multi-protein assembly triggered by diverse danger-associated signals, i...

Yan Cheng, Ji Wang, Zheng-Jie Fan et al. · 0 citations
Review Open access Aug 2026

Immunological Mechanisms of the Gut–brain–cardiovascular Axis in Coronary Heart Disease with Comorbid Anxiety and Depression

Coronary heart disease (CHD) is frequently accompanied by anxiety and depression, conditions that markedly worsen cardiovascular outcomes. Increasing evidence indicates that immune dysregulation, driven by gut microbiota alterations, plays a central role in linking psychological disorders with cardiovascular pathology...

Yi-Wei Xu, Xiaohua Chen · 0 citations

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