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Open access Oct 2026

Early-onset colorectal cancer burden in China from 1990 to 2023: a systematic analysis based on the Global Burden of Disease Study 2023

Early-onset colorectal cancer (EOCRC) impairs the health of China’s working-age population and causes substantial socioeconomic costs. National long-term epidemiological data integrating trend segmentation, risk attribution and medium-term forecasting for domestic EOCRC remain insufficient. This study analysed Chin...

Hai-Jian Wei, Hao Wu, Shuai Wang et al. · 0 citations
Open access Aug 2026

CARD10 deficiency attenuates myocardial infarction associated with enhanced cardiac fibroblast senescence

It is suggested that CARD10 deficiency is associated with enhanced fibroblast senescence and improved post-MI remodeling, potentially involving mitochondrial dysfunction and PI3K/AKT signaling, highlighting CARD10 may represent a promising target for the treatment of MI.

Yueyue Xu, Yi-Wei Yao, Yue-Yun Zhou et al. · 0 citations

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