Yi-Wen Sheng

Ubiquitination regulation in coronary microcirculation dysfunction: focus on the endothelial cells

Basic and clinical research on coronary microvascular disease (CMD) has spanned half a century. As a pathogenesis independent of epicardial coronary stenosis, CMD has become a major hotspot in cardiovascular medicine. Ubiquitination, a vital post-translational modification in eukaryotic cells, precisely regulates targe...