Improved efficacy of Orelabrutinib plus Rituximab, Temozolomide and High-Dose Methotrexate (RMOT) vs. RMT in untreated primary CNS lymphoma: A matched analysis
Primary central nervous system lymphoma (PCNSL) is a rare, aggressive malignant tumor with poor prognosis, and the optimal standard treatment remains undefined. This study aimed to compare the efficacy and safety of rituximab, high-dose methotrexate plus temozolomide (RMT regimen) and orelabrutinib plus RMT (RMOT...