Author

Yi-Xin Wang

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Open access Sep 2026

Epiberberine and Palmatine Alleviate Staphylococcus aureus-Induced Acute Lung Injury by Modulating Host Inflammatory Responses Involving Src/Syk Signaling

Acute lung injury (ALI) caused by bacterial infection is largely driven by dysregulated host inflammatory responses, highlighting the need for host-directed therapeutic strategies. In this study, we investigated alkaloids derived from Coptis chinensis , focusing on epiberberine and palmatine, in both in vivo and...

Pei-Pei Ren, Zhi-Guo Gong, Yi-Xin Wang et al. · Inflammation · 0 citations

Open access Sep 2026

The crosstalk between alternative splicing and histone ubiquitination modulates fast chemical reprogramming to pluripotency.

Cellular reprogramming has revolutionized regenerative medicine. Recently, we develop a fast chemical reprogramming (FCR) system; however, the underlying molecular mechanisms remain largely unknown. Here, we investigated the dynamics of RNA-binding protein (RBP) expression and alternative splicing (AS) events in the FC...

Qiang Deng, Xi Chen, Yu-Han Li et al. · Stem Cell Reports · 0 citations