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Yi-Yan Pei

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Clinical trial Open access Sep 2026

Neoadjuvant chemoimmunotherapy with afatinib for locally advanced head and neck squamous cell carcinoma (neoCHANCE-2): an open-label, single-arm, phase 2 study

Abstract Background While immune checkpoint inhibitor-based neoadjuvant therapy shows promise in locally advanced head and neck squamous cell carcinoma (LA-HNSCC), the optimal regimen has yet to be established. We report, for the first time, a neoadjuvant treatment that combines chemotherapy with dual blockade of the p...

Zhi-Gong Wei, Hui-Jiao Chen, De-Juan Wang et al. · 0 citations

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