Author

Yi Yang

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Review Open access Oct 2026

Deep brain stimulation and spinal cord stimulation for chronic disorders of consciousness: a decade of clinical evidence, mechanistic insights, and critical appraisal

Deep brain stimulation (DBS) and spinal cord stimulation (SCS) have been investigated for over four decades as neuromodulatory treatments for chronic disorders of consciousness (DOC), including the vegetative state/unresponsive wakefulness syndrome (VS/UWS) and the minimally conscious state (MCS), for which no disease-...

Dong-Sheng Liu, Kai-Wai Yang, Jian-Lei An et al. · Frontiers in Human Neuroscie... · 0 citations

Open access Aug 2026

Real-world clinical characteristics of motor disorders for personalised brain-computer interfaces: phenotypic insights from a specialised clinic.

Motor dysfunction caused by neurological disorders such as stroke, spinal cord injury and amyotrophic lateral sclerosis has become a major global public health issue. Conventional rehabilitation approaches yield limited efficacy, highlighting the urgent need for innovative therapies. Brain-computer interface (BCI) tech...

Xiao-Ke Chai, Zhiyao Zheng, Nan Wang et al. · Stroke and vascular neurolog... · 0 citations

Review Open access Sep 2026

Neural Circuit Mechanisms of Disorders of Consciousness and Potential Therapeutic Targets of Brain Stimulation

ABSTRACT Background Disorders of consciousness (DoC) lack an integrated framework to guide neuromodulation. This review updates three hierarchical frameworks—ARAS, mesocircuit, and ICNs—and maps therapeutic targets within each. Methods We synthesized recent neuroanatomical, optogenetic, neuroimaging, and clinical trial...

Yi-Chen Zhou, Tian-Qing Cao, Si-Peng Zhu et al. · CNS Neuroscience & Therapeut... · 0 citations