Open access
Jul 2026
An enzyme-specific protein language model for catalytic property prediction
This manuscript introduces EnzGFM, an enzyme-specific hybrid model that improves both accuracy and efficiency across multiple prediction tasks and, together with the EnzGFM-Agent pipeline, demonstrates the ability to identify experimentally validated beneficial variants while reducing screening effort.
Chong Wang, Mengyao Li, Shaolei Geng et al.
· Nature Communications · 0 citations