Author

Yi Zhang

2 papers indexed here

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Review Open access Sep 2026

The plasticity and metabolic reprogramming of macrophage in ulcerative colitis

Macrophages exhibit phenotypic plasticity, which plays a role in driving tissue injury and promoting mucosal repair in ulcerative colitis (UC). Intestinal macrophages originate from both embryo-derived resident cells and circulating monocytes. Macrophage polarization influences inflammatory responses and is regulated b...

Yi Zhang, Ding-Quan Yang, Jun-Nan Jiang et al. · Frontiers in Immunology · 0 citations

Review Open access Aug 2026

Liver microenvironment-driven immunosuppressive niche in colorectal cancer liver metastasis and its therapeutic remodeling

Colorectal cancer liver metastasis is the most frequent and clinically important pattern of distant spread in colorectal cancer and remains a major determinant of poor prognosis and treatment failure. In the era of immunotherapy, liver metastasis has emerged as an organ-specific barrier to effective antitumor immune re...

Zi-Jing Liu, Jia Liu, Sheng-Shan Xu et al. · Frontiers in Immunology · 0 citations