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Open access Aug 2026

Female vulnerability to microvascular transport dysfunction emerges early across the Alzheimer's disease continuum

We tested whether quantitative transport mapping (QTM)‐derived perfusion velocity would detect earlier and more sex‐specific microvascular alterations than cerebral blood flow (CBF) across the Alzheimer's disease (AD) continuum.

Man-Xi Xu, Yian Gao, Peiling Ou et al. · 0 citations
Open access Aug 2026

MRI-derived oxygen extraction fraction is associated with cognitive impairment in cerebral small vessel disease.

BACKGROUND Conventional MRI markers of cerebral small vessel disease (CSVD) capture accumulated structural injury but may not fully reflect ongoing physiological dysfunction associated with cognitive impairment. AIMS We investigated whether MRI-derived oxygen extraction fraction (OEF), a non-invasive marker of cerebr...

Chaofan Sui, Meng Li, Qihao Zhang et al. · 0 citations

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