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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Yige Yang

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Aug 2026

Reprogramming Enfumafungin Biosynthesis for High-Titer Production in the Endophytic Fungus Hormonema carpetanum ATCC 74360

Enfumafungin is the essential precursor for the FDA-approved antifungal agent Ibrexafungerp, yet its production is hindered by low yields, restrictive solid-state fermentation, and the genetic intractability of its producer strain, Hormonema carpetanum ATCC 74360. Here, we developed a CRISPR/Cas9-mediated platform th...

Jing Wo, Hai-Peng Yu, Yige Yang et al. · 0 citations

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