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#generative ai Dataset Open access Oct 2026

Activity-feature-guided discrete diffusion with direct preference optimization for strong promoter design in actinomycetes

Strong promoters enhance transcriptional output and are important for natural product discovery and industrial strain engineering in actinomycetes. However, host-compatible strong promoters are scarce, and AI-assisted design of high-activity promoters remains challenging. Here, we develop DPOCondD3PM, an activity-featu...

Yijun Gu · 0 citations

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