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Sep 2026

Cognitive heterogeneity in major depressive disorder: Neuroimaging, transcriptomic, and neurotransmitter profiles.

This study provides a data-driven characterization of cognitive heterogeneity in MDD, identifying two cognitive dimensions spanning from relative preservation to widespread impairment, and provides preliminary biological context for interpreting cognitive heterogeneity in MDD.

Yu-Shun Yan, Jia'ao Yu, Liang Zuo et al. · 0 citations
Review Aug 2026

Multimodal neuroimaging changes and their behavioral, genetic, and neurotransmitter correlates in electroconvulsive therapy for major depressive disorder.

Findings suggest the left AG is a key region mediating ECT's effects, and indicates that ECT may exert its antidepressant action by modulating neurotransmitter systems, offering insights into the neural and molecular basis of its therapeutic efficacy in MDD.

Ruifeng Shi, Yi-Kai Dou, Ying He et al. · 0 citations

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