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Yiming Zhou

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Preprint Aug 2026

TransNRank: Towards Accurate Neoantigen Ranking with Transformer

A novel deep learning framework based on Transformer, coined as TransNRank, that streamlines the prediction pipeline but also sets a new state-of-the-art for neoantigen discovery, with broad implications for accurate immuno-oncology.

Zhiyin An, Yue-Nan Hou, Shumeng Duan et al. · 0 citations
Open access Jul 2026

Manganese-Polydopamine Nano-Immunomodulator Synergistically Activates the STING Pathway and Pyroptosis for Renal Cell Carcinoma Immunotherapy 2308359

In vivo, PDA-Mn-HA NPs not only inhibited RCC tumor growth but also increased immune cell infiltration, particularly cytotoxic T cells, reshaping the tumor microenvironment to promote anti-tumor immunity.

Yiming Zhou, Yue Pan, Yufei Du · 0 citations
Open access Jul 2026

Antibody-mediated CAR T Platform for Targeting Tumor Cells and the Tumor Microenvironment 2301697

A dual-targeting strategy disrupted the TME-induced immune suppression, reduced collagen deposition, and boosted T cell activity, resulting in notable tumor growth inhibition and prolonged survival in both subcutaneous and orthotopic pancreatic cancer models.

Yiming Zhou, Jian-Chuan Wang, Yufei Du · 0 citations

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