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Aug 2026
A novel deep learning framework based on Transformer, coined as TransNRank, that streamlines the prediction pipeline but also sets a new state-of-the-art for neoantigen discovery, with broad implications for accurate immuno-oncology.
Zhiyin An, Yue-Nan Hou, Shumeng Duan et al.
· 0 citations
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Jul 2026
The findings suggest that mRNab-LNPs offer a promising alternative to current therapies, providing a safer, more efficient approach to treating autoimmune diseases by resetting the humoral immune system.
Yiming Zhou, Jinjin Chen, Chi-Peng Guo
· Journal of Immunology · 0 citations
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Open access
Jul 2026
In vivo, PDA-Mn-HA NPs not only inhibited RCC tumor growth but also increased immune cell infiltration, particularly cytotoxic T cells, reshaping the tumor microenvironment to promote anti-tumor immunity.
Yiming Zhou, Yue Pan, Yufei Du
· Journal of Immunology · 0 citations
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Open access
Jul 2026
A dual-targeting strategy disrupted the TME-induced immune suppression, reduced collagen deposition, and boosted T cell activity, resulting in notable tumor growth inhibition and prolonged survival in both subcutaneous and orthotopic pancreatic cancer models.
Yiming Zhou, Jian-Chuan Wang, Yufei Du
· Journal of Immunology · 0 citations
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