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Yin-Qin Cheng

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Open access Sep 2026

Hepatocyte SLC31A1-dependent copper accumulation contributes to hepatic glucose and lipid metabolic disturbances through AMPKα1 inactivation

Hepatic insulin resistance and fat accumulation are common features of metabolic syndrome, obesity and type 2 diabetes (T2D). However, whether the copper importer SLC31A1 has a role in diabetes-associated hepatic metabolic disorders remains unknown. Thus, we studied the role of hepatocyte SLC31A1 in HFD/STZ-induced T2D...

Yin-Qin Cheng, Min Wei, Le Yang et al. · 0 citations

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