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Author

Yin-Tzer Shih

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Oct 2026

Inter-isolate similarity networks reveal task-dependent graph signal for antimicrobial resistance prediction from MALDI-TOF mass spectra.

Antimicrobial resistance (AMR) prediction from matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectra is typically formulated as instance-wise classification, even though clinical isolates are naturally related by spectral similarity. We ask whether isolate-level similarity carries AMR info...

Yi-Hsin Chen, Yin-Tzer Shih · 0 citations
Open access Sep 2026

Branch-Wise Regularization for Heterogeneous GNN-Based MALDI-TOF AMR Prediction with Biomarker-Consensus Edges

This paper predicts antimicrobial resistance (AMR) from matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectra using DRIAMS, evaluated across 13 species-antibiotic datasets spanning sensitive/resistant imbalance ratios of 2.95:1 to 141.21:1 and raw spectral similarities of 0.9166–0.9946. We...

Wan-Yu Tsai, Yin-Tzer Shih, Y.-H. Chen · 0 citations

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