Review
Open access
Jul 2026
The SCF/KIT signaling pathway in multisystem diseases: Mechanisms and therapeutic targeting
The stem cell factor (SCF)/KIT signaling axis regulates the survival, proliferation, differentiation, and migration of hematopoietic stem and progenitor cells, mast cells, interstitial cells of Cajal, germ cells, and melanocytes through multiple downstream pathways, including PI3K/AKT and RAS/MAPK. Its biological and p...
Rui-Die Ma, Xue-Liang Wang, Ying-Bing Mei
· Science in progress · 0 citations