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Author

Ying-Chao Han

2 papers indexed here

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Open access Sep 2026

Macro–Micro structural integration for characterizing severity-related structural alterations in mild cognitive impairment

Mild cognitive impairment (MCI) is a clinically heterogeneous condition characterized by substantial variation in structural abnormalities and cognitive impairment. However, existing neuroimaging-based approaches are limited by insufficient modeling of coordinated gray–white matter alterations and vulnerability to site...

Qi-Chen Zhang, Di Zhang, Rui-Xia Zhou et al. · 0 citations
Open access Sep 2026

Beyond statistical thresholds: Mapping sequential ATN cascade transitions via brain structural topography in Alzheimer’s disease

Alzheimer’s disease is widely conceptualized as a biological continuum initiated by amyloid-β (Aβ) accumulation, followed by tau aggregation and neurodegeneration. Although the ATN framework is commonly used to define disease stages, its static biomarker categories may not fully capture the dynamic pathological transit...

Dong Wang, Shao-Zhen Yan, Rong-Shen Zhou et al. · 0 citations

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