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Aug 2026

Investigating cross-organism prediction of prokaryotic essential proteins using unsupervised language model and ensemble strategy.

This study proposes DeepPEP, a large language model-based framework designed to reliably transfer essential protein annotations between distantly related organisms and suggests that DeepPEP is a powerful strategy for prokaryotic essential protein prediction.

Ying Du, Zhikang Liu, Jing Wan · 0 citations