TOPIC
Teprotumumab is the first FDA-approved biologic for moderate-to-severe thyroid eye disease (TED). Although efficacy has been established in randomized controlled trials (RCTs), real-world studies (RWS) have reported different efficacy and safety patterns, supporting an updated synthesis.
CLINICAL RELEVANCE
A co...
Ai-Min Sun, Xing Wang, Jun-Yu Wang et al.· American journal of ophthalm...· 0 citations
The findings provide biological insights that may inform targetable, lipid-oriented nutritional and/or pharmacological strategies to modulate foetal growth and development, with the goal of optimising clinical outcomes for both mother and child.
Whether data-driven clustering based on metabolomic biomarkers could define distinct prediabetes subtypes with differential type 2 diabetes, cardiovascular disease, and chronic kidney disease risk is examined and metabolomics-based subtypes may improve risk stratification and support precision prevention strategies.
Fei Chen, Yang Zhang, Weihao Wang et al.· Diabetes· 0 citations
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