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Author

Ying Gao

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Review Sep 2026

Teprotumumab for Thyroid Eye Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Real-World Studies.

TOPIC Teprotumumab is the first FDA-approved biologic for moderate-to-severe thyroid eye disease (TED). Although efficacy has been established in randomized controlled trials (RCTs), real-world studies (RWS) have reported different efficacy and safety patterns, supporting an updated synthesis. CLINICAL RELEVANCE A co...

Ai-Min Sun, Xing Wang, Jun-Yu Wang et al. · 0 citations
Open access Aug 2026

Trans-omics integration underscores distinct roles of polyunsaturated phospholipids in bidirectional offspring birth weight deviations

The findings provide biological insights that may inform targetable, lipid-oriented nutritional and/or pharmacological strategies to modulate foetal growth and development, with the goal of optimising clinical outcomes for both mother and child.

Jia Zheng, Sin-Man Lam, Wei Ling Florence Lim et al. · 0 citations
Open access Aug 2026

Metabolomics-Defined Subtypes of Prediabetes and Risk of Cardiovascular-Kidney-Metabolic Outcomes

Whether data-driven clustering based on metabolomic biomarkers could define distinct prediabetes subtypes with differential type 2 diabetes, cardiovascular disease, and chronic kidney disease risk is examined and metabolomics-based subtypes may improve risk stratification and support precision prevention strategies.

Fei Chen, Yang Zhang, Weihao Wang et al. · 0 citations

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