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Ying-Jie Wang

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Open access Sep 2026

Regioselective Insertion of Diazo Compounds Into 3‐Hydroxyisoindolinones for the Synthesis of Isoquinolones

Both 3‐hydroxyisoindolinones and isoquinolones are structural motifs found in many natural alkaloids, and their derivatives exhibit a wide range of therapeutic applications. Herein, we report the direct conversion of 3‐hydroxyisoindolinones into isoquinolones via a diazo ester insertion reaction. This transformation in...

Yi-Han Gao, Xiao-Fei Chen, Ying-Jie Wang et al. · 0 citations

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