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Author

Ying Liu

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Oct 2026

Activity over Abundance: ADAMTSL4 Unlocks Latent TGFβ1 in Cancer Cachexia.

Cancer cachexia is increasingly recognized as a coordinated, tumor-induced, unsustainable alteration in interorgan communication. Machado and colleagues identify a new molecular mechanism that promotes cachexia, in which tumor-secreted ADAMTSL4 drives tissue wasting by promoting local activation of latent TGFβ1, reveal...

Ying Liu, T. Janowitz · 0 citations

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