Review
Open access
Sep 2026
The GPR183-oxysterol axis in cancer: immune trafficking, spatial organization, and therapeutic potential
G protein-coupled receptor 183 (GPR183; also known as EBI2, Epstein-Barr virus-induced G-protein-coupled receptor 2) has emerged as a central regulator linking 7α,25-dihydroxycholesterol (7α,25-OHC) gradients to immune cell trafficking and tissue organization. In this review, we synthesize the structural, physiological...
Hai-Hui Zhuang, Feng-Lin Li, Shuang-Yue Li et al.
· Frontiers in Immunology · 0 citations