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Ying Shen

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Open access Sep 2026

IRF1-mediated thioredoxin (TXN) protects multiple myeloma cells from ferroptosis through remodeling of PUFA-containing phospholipids

Thioredoxin (TXN), a central redox regulator, is identified as a ferroptosis suppressor associated with poor prognosis in MM patients and the IRF1-TXN axis is established as a potential therapeutic target for overcoming ferroptosis resistance and improving MM treatment outcomes.

Jia-Xi Liu, Ji-Yu Miao, Yang Lv et al. · 0 citations

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