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Open access Sep 2026

Efficacy and Safety of Recibokibart, an Interleukin-36 Receptor Antibody, in Generalized Pustular Psoriasis: A Phase 2 Randomized Trial.

BACKGROUND Generalized pustular psoriasis (GPP) is a rare, severe inflammatory skin disease characterized by acute flares. Recibokibart is a humanized IgG1 monoclonal antibody targeting the interleukin-36 (IL-36) receptor. In a phase 1b open-label study, a single intravenous dose of recibokibart was associated with an...

Bao-Qi Yang, Yu-Zhen Li, Yu Wang et al. · 0 citations
Open access Sep 2026

Age-stratified correlations between atopic dermatitis severity and biomarkers: hypercoagulability as a key indicator of severity in older adults.

Background Atopic dermatitis (AD) is a chronic skin disorder with systemic inflammation. Previous studies have focused primarily on its allergic characteristics, whereas the accompanying systemic inflammation and potential hypercoagulable state, particularly across different age groups, have received insufficient atten...

Yi-Fan Zhang, Zheng-Hui Yang, Ying-Ran Zhao et al. · 0 citations

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