Guanidine hydrochloride-induced transport mode transition of β-cyclodextrin-amantadine inclusion complexes revealed by a single α-hemolysin nanopore.
Cyclodextrin inclusion complexes are widely used in drug delivery systems because they can improve the solubility and stability of drug molecules. However, the stability and transport mechanism of host-guest complexes during transport processes remain poorly understood. In this work, a single α-hemolysin (α-HL) nanopor...