Sep 2026
pH-Responsive Hydrogel-Mediated Transdermal Co-delivery of Triamcinolone Acetonide and 5-Fluorouracil for Hypertrophic Scar Treatment via Regulating Macrophage Polarization and Exerting Antifibrotic Effects.
Hypertrophic scar (HS) is a fibrotic disorder caused by imbalanced tissue repair after skin injury. Its core features include persistent inflammation and excessive collagen deposition. Current clinical treatments are limited by poor efficacy, severe local adverse reactions, and low transdermal delivery efficiency of to...
Shi-Sheng Chen, Yuan-Yuan Hu, Hong-Ping Ge et al.
· ACS Applied Materials and In... · 0 citations