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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Ying Xing

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Oct 2026

ZC3H13-Mediated m6A Modification of TRIM16 Suppresses EndMT and Atherosclerosis by Destabilizing Ang2 and Inhibiting the TLR4/NLRP3 Pathway.

The RNA methyltransferase zinc finger CCCH-type containing protein 13 (ZC3H13) is downregulated in atherosclerosis (AS), but its functional mechanism remains unclear. Endothelial-mesenchymal transition (EndMT) is a core pathological driver of endothelial dysfunction in AS. This study aimed to investigate the biological...

Chen Wang, Ying Xing, L.-V. Wang et al. · 0 citations
Jul 2026

p53 hotspot mutants attenuate CTL-mediated tumor cell killing through a novel ALKBH5-YTHDF3-PD-L1 pathway

It is found that the oncogenic effect of mutant p53 in vivo is dependent on the tumor immune microenvironment, and restoration of ALKBH5 activation or inhibition of the m6A modification-YTHDF3 axis could potentially reactivate immune surveillance and eliminate tumors harboring mut-p53.

Zhuan Ju, Xiang Zhang, Wen-Jie Zuo et al. · 0 citations

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