Open access
Sep 2026
Targeting BIRC6 rejuvenates hematopoietic stem cell aging and immunosenescence
Immunosenescence represents a central hallmark of organismal aging, characterized by a progressive decline in immune function, which compromises host defense and accelerates systemic aging. Hematopoietic stem cell (HSC) aging is a key contributor to this process, characterized by aberrant expansion, myeloid-biased diff...
Wei-Nian Liao, Fang-Ze Shao, Shao-Yan Wang et al.
· Signal Transduction and Targ... · 0 citations