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Author

Ying-Ying Guo

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Review Open access Aug 2026

The ER–Golgi intermediate compartment: a central hub integrating membrane trafficking and stress responses

The endoplasmic reticulum–Golgi intermediate compartment (ERGIC) is a dynamic membrane system at the ER–Golgi interface, traditionally viewed as a transient station for COPII- and COPI-dependent trafficking. Emerging evidence redefines the ERGIC as a stress-responsive regulatory hub that integrates membrane trafficking...

Ying-Ying Guo, Jian-Fei Zheng, Lei Liu et al. · 0 citations
Review Open access Aug 2026

Non-histone protein L-lactylation in cancer: a metabolic switch for immune evasion and therapeutic resistance

This work defines the spatially compartmentalized catalytic network governing this process, detailing how nuclear EP300/CBP, cytosolic AARS1, and mitochondrial AARS2 mediate stereospecific targeted modifications.

Ying-Ying Guo, Lanyang Gao, Shundan Li et al. · 0 citations

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