Open access
Oct 2026
Discovery and optimization of A 2-phenyl-1,2,4-triazolidin-3-one scaffold as potent ferroptosis inhibitors for hepatoprotection.
TZN-23 effectively alleviated concanavalin A (ConA)-induced acute liver injury in mice by inhibiting ferroptosis, and served as potent tool molecules for investigating ferroptosis and offering potential therapeutic strategies for ferroptosis-related diseases.
Heng-Yi Cao, Ying Huang, Gui-Hua Yang et al.
· European journal of medicina... · 0 citations