Author

Ying-Ying Zhang

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Review Open access Sep 2026

Physical Therapy for Treatment-Resistant Depression A Comprehensive Review of Efficacy, Safety, and Evidence Grading

Abstract Major depressive disorder (MDD) is a common psychiatric illness that is primarily treated with antidepressant medications in clinical practice. Depression that responds poorly to antidepressant therapy is referred to as treatment-resistant depression (TRD). However, the definition and pathogenesis of TRD are u...

Wen-Xia Jiang, Hao-Ran Xing, Yun-Cheng Bai et al. · Neuropsychiatric Disease and... · 0 citations

Open access Sep 2026

A single-nucleus transcriptome atlas of cell diversity in human prefrontal cortex across the postnatal lifespan

Brain aging is a major risk factor for cerebrovascular and neurodegenerative diseases, yet continuous cell-type changes across the human lifespan remain incompletely defined. Here, we integrate 15 prefrontal cortex (PFC) snRNA-seq datasets from 158 neurologically healthy donors (19–101 years) to construct an atlas of...

Rui-Ze Niu, Meng-Yuan Zhang, Zhi-Lan Yang et al. · npj Aging · 0 citations