Open access
Jul 2026
Machine Learning Gap-Fills Missing Transporter Kinetics in Biosystems Across Scales
The first compound-protein interaction machine learning model of transporter Vmax and Km, MMTKPred is developed, which captures the effects of point mutations and substrate changes on transporters and effectively models metabolite transport spanning from molecular to multi- species scales.
Sizhe Qiu, Zhangyu Guo, Weiming Tu et al.
· bioRxiv · 0 citations