Selective Kv1.3 inhibition promotes M2 microglial polarization, accelerates hematoma resolution, and improves neurological recovery following collagenase-induced spontaneous intracerebral hemorrhage in mice
ABSTRACT Background and Aim: Spontaneous intracerebral hemorrhage (sICH) is a devastating subtype of stroke characterized by high mortality, severe neurological disability, and limited effective pharmacological treatment. Secondary brain injury following sICH is largely driven by excessive neuroinflammation, in which a...