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Author

Yining Xie

2 papers indexed here

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Review Sep 2026

Decoding SUMOylation as a metabolic stress sensor in aging and age-related disorders: mechanisms, tissue specificity and therapeutic potential.

This synthesis provides a framework for understanding how SUMOylation links metabolic stress to tissue-specific aging trajectories and therapeutic potential and evaluates emerging translational approaches that highlight both the opportunities and challenges of targeting SUMO-regulated stress responses in aging.

Xin-Yue Liu, Shuang Chen, Dong-Can Liu et al. · 0 citations
Review Open access Jul 2026

Endocrine-metabolic imbalance drives osteoarthritis: From whole-joint pathobiology to precision therapy (Review)

Osteoarthritis (OA) is a chronic degenerative joint disease closely associated with aging and metabolic dysfunction, characterized by cartilage degeneration, synovial inflammation, aberrant subchondral bone remodeling, pain and progressive functional impairment. Beyond mechanical loading, accumulating evidence indicate...

Ruhui Yang, Haimin Zeng, Qi Xiao et al. · 1 citation

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