Author

Yinyin Liu

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Open access Aug 2026

Substitution-induced allosteric activation of coagulation factor IX as a potential alternative hemophilia A treatment strategy.

Targeted modification of regions surrounding the FIXa active site enables allosteric activation, providing a potential foundation for novel bypassing strategies in hemophilia A therapy.

V. Strijbis, K. Cheung, D. Gobbo et al. · Thrombosis Research · 0 citations