Open access
Aug 2026
Enhancing Adeno-Associated Virus 2 Capsid Engineering Through Co-Evolutionary Coupling.
This study highlights the potential of using evolutionary coupling analysis to guide AAV capsid engineering, suggesting that conservative mutations informed by evolutionary data can improve AAV stability and efficacy.
Sirimar Laosinwattana, Yiwen Li, Braulio Carrillo Sanchez et al.
· Biotechnology and Bioenginee... · 0 citations