Open access
Sep 2026
Potential of β-catenin inhibitors as a novel therapeutic strategy for PIK3CA/CTNNB1 double-mutant endometrial cancer
Endometrial cancer (EC) is one of the most prevalent gynecological malignancies. EC is characterized by limited therapeutic options and a substantial unmet medical need, particularly in advanced or metastatic stages. Although a high prevalence of concurrent PIK3CA and CTNNB1 mutations has been reported in patie...
Takehiro Nakao, R. Kamata, Hitoshi Saito et al.
· Cell Death Discovery · 0 citations