Author

Yong-Ang Li

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Oct 2026

Juglone induces GSDME-mediated pyroptosis by targeting HSP90α ATPase domain to promote STAT3 degradation in glioblastoma multiforme.

Glioblastoma (GBM) is a highly aggressive primary brain tumor with grim overall median survival, and its therapeutic efficacy is severely limited due to drug resistance. Therefore, developing effective and safe chemotherapy regimens is urgently required. Juglone, a natural bioactive constituent derived from traditional...

Hao Wu, Shuai Chen, Jia-Wen Li et al. · Toxicology and Applied Pharm... · 0 citations

Review Open access Jul 2026

Microbiota–innate immune crosstalk drives atherosclerosis: mechanisms, disease progression, and emerging therapeutic strategies

The microbiota–innate immune axis provides a novel conceptual framework for understanding atherosclerosis pathogenesis and represents a promising target for future disease prevention, risk stratification, and precision therapeutics.

Yong-Ang Li, Jin-Heng Zhu, Mingkui Huang et al. · Frontiers in Immunology · 1 citation