Signal transducers and activators of transcription (STAT), as a core component of the Janus kinase (JAK)/STAT signaling pathway, play a vital regulatory role in the innate antiviral immunity and immune signal transduction in
Scylla paramamosain
. To enable comprehensive biological studies, we developed and validate...
Ji-Yue Hu, Qian-Ying An, Shao-Ni Fu et al.· Israeli Journal of Aquacultu...· 0 citations
Vibrio harveyi is a major bacterial pathogen in marine aquaculture, posing a serious threat to fish health. IRF1 is a conserved regulator of teleost immunity; however, the transcriptional regulatory networks associated with IRF1 during bacterial infection remain incompletely understood. To characterize CaIRF1-associate...
Guo-Tao Wang, Gui-Sen Chen, Ting Wu et al.· Developmental and Comparativ...· 0 citations
These results validated the canonical heterodimerization of the short-chain CaCRFB5 with both long-chain subunits (CaCRFB1 and CaCRFB2) as well as a noncanonical interaction of CaCRFB1/CaCRFB2, suggesting a more intricate receptor pairing in teleosts.
Han Zhang, Ting Wu, Ying Chen et al.· Developmental and Comparativ...· 0 citations
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