Author

Yong-Cheng Chen

2 papers indexed here

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Open access Sep 2026

Persistent Zn2+ Influx‐Mediated Deacetylation of ANXA2 Regulates the “Zn2+‐Autophagic Flux” and Alleviates Intervertebral Disc Degeneration

ABSTRACT Intervertebral disc degeneration (IVDD) is an age‐related disease accompanied by disrupted mitochondrial homeostasis and defective autophagy. Cellular senescence induces ion imbalance, which leads to mitochondrial damage and suppressed autophagic flux; nevertheless, the molecular mechanism underlying this proc...

Yu-Xin Jin, Yong-Cheng Chen, Yi-Hao Xie et al. · Advancement of science · 0 citations

Sep 2026

Synchronous Metabolic Interference and Immune Reprogramming by a Self-Assembled Bismuth–Phenolic Nanoparticle against Pseudomonas aeruginosa -Induced Infections

Effective eradication of Pseudomonas aeruginosa (P. aeruginosa) infection remains challenging due to its multifaceted antibiotic resistance mechanisms and biofilm-associated protection. Furthermore, inflammatory dysregulation within the infected microenvironment compromises both antibacterial efficacy and tissue repa...

Hao-Jie Chen, Rou-Ye Wang, Fang Liu et al. · ACS Nano · 0 citations