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Author

Yong-Guy Kim

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Open access Aug 2026

Antibiofilm and Anti-Hyphal Activities of Halogenated Benzophenones Against Azole-Resistant Candida albicans

Findings indicate that multi-halogenated benzophenones act primarily as anti-virulence agents targeting biofilm formation and hyphal development and identify benzophenone scaffolds as promising leads for developing novel antibiofilm strategies against azole-resistant Candida infections.

Juyeon Jo, Ziyad Abdelaal, Yong-Guy Kim et al. · 0 citations
Jul 2026

Lauric Acid- and BDSF-Derived N-Acyl Sulfonamides as Potent Antibiofilm and Antivirulence Agents against Staphylococcus aureus.

Low toxicity in plant, nematode, and mammalian models highlights bioisosteric N-acyl sulfonamides as promising antivirulence scaffolds for combating S. aureusBiofilm-associated Staphylococcus aureus infections remain difficult to treat using conventional antibiotics.

Yong-Guy Kim, Michelle O'Driscoll, Conor Horgan et al. · 0 citations
Jul 2026

Dihalogenated indoles with antimicrobial activity against C. acnes and polymicrobial biofilms.

It is demonstrated that a dihalogenated indole reduces lipase-associated virulence related phenotypes in C. acnes and suppresses biofilm formation in skin-relevant environments, supporting further investigation of this scaffold as a therapeutic strategy targeting acne-associated microbial physiology.

S. Angulmaduwa, G. G. Roshan Pradeep Ratupaskatiye, Yong-Guy Kim et al. · 1 citation

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